For the reasons of Randy Orton's gimmick, I could see Orton facing Edge in a TLC match.
Did I say I wanted that to happen? No. I'm just pointing out the distinct possibility of what could happen, because of Orton's gimmick. And frankly, because of that gimmick he has, that would be why he'd want to face Edge in a TLC match. Because that is Edge's "legacy" (current and a part of it) he'll leave behind when he finishes his career in the WWE.
With Randy's gimmick, he'd have to have a reason to face off against Edge in a singles match. That would be it. As Edge is very successful in that match, both as a tag team member and a singles member. Hence, I could see it happening. I don't really care for it, but unless Randy's gimmick changes when there's no more legends around, I'm expecting it to happen.