There are a few that I've seen -- Mary Brown's still has a few stores open, although not as many as they did when I was in university. Dixie Lee is another chicken franchise; their stores are mostly in smaller towns. I remember from my childhood that we always used to pass one on the way to my grandmother's house in Napanee.
I also remember there being a TGI Fridays in the Clifton Hill area in Niagara Falls the last time I was there. It's the only Fridays I've ever seen in Canada, though.
There's two TGIFridays in Niagara Falls now. The only Canadians that go their are the employee's or people going for a drink. No one goes in there for the food because how expensive it is. If you want to pay pricey food, The Keg is around the corner.
Burger King is across town and same with Quizno's and Subway.