Are you referring to "The Break-Up" as the other bomb? I assume so.
I think this means that at least one of them (most likely Owen) will need to take a drastically different role then what they normally do. "Owen Wilson as Owen Wilson" isn't going to fly much longer.
I meant "You Me and Dupree." Maybe it didn't bomb as badly as I thought, but then you have to imagine what the Wilson Brothers are asking per movie now seeing as how the rest of the Frat Pack have been a role for a few years now, particularly Ferrel and Vaughn.
You, Me and Dupree was budgeted at 54 mil. It's going to easily turn a nice profit. The movie was pretty much sold on Owen Wilson's name, and I think the total gross will end up being pretty good.