You hike the ball by moving the remote up and at least for now it only gives you EARLY SNAP warnings if you do it too soon..itd be a bitch if they penalized you for a false start every time.
Running is all done by the stick on the nunchuck, Juke by moving the nunchuck (left or right), stiff arm by moving the remote (left or right). Passing is pretty simple, just flick the remote u, slow is a lob pass and faster is a bullet pass. Receivers selected with the d-pad. To have catch the ball/intercept on defense you have to raise both the remote and the nunchuck up at the same time. Audibles are called by pointing at the QB and pressing A (which stops the clock for some reason).
Kicking is kinda hard, as you have to start the remote pointed down and flick it up and the speed you move it up gives you the power, but if you twist the remote even slightly it puts slice into the kick either way you twisted the remote.
The most rediculous control though is for a fair catch, where you have to wave the remote up in the air left to right to left to righ like you were actually signalling for a fair catch. Ive not been able to do that in game despite mastering it in the Learn Madden portion and a little less bad in Zelda..
All in all like I said, offense is easy to figure out but for some reason defensive control isn't as good.
as a side note, lots of people are complaining that the nunchuck isn't as responsive with motion controls...I noticed that a lot in the boxing game of W!! sports, as my left punches seemed to register only about 2/3rds of the time.