can't delete a file

[lomasmoney]

After downloading the Rundown off Bit Torrent, I deleted it from off my desktop and for some reason it won't let me delete the file from the Recycle Bin. It comes up with an error like can't delete Dc65: This file is being used by another program or someone else. I also have the same problem with a file that was partially downloaded through AIM before my buddy's computer crashed. These are both really big files, 500 mb + that i want to get off my computer. Can anyone help. I'm running Windows XP Home and I tried going into safe mode to delete the file and that didn't work

[MrRant]

If after restarting you can't delete them then they could contain a virus.

[razazteca]

Can you change the association of the file then try to delete it?

[Guest theoldxpac]

I get this problem with files from kazaa sometimes, and i have to delete them through kazaa itself, not from my documents, but fucks nos how to do this one.