Louisville played Kentucky in the first game of the year at Kentucky. If Louisville wins all their other game like they did last week then no one will remember the week 1 game, just as everybody seemingly forgot how USC struggled against Stanford and some other teams after the Orange Bowl.
It doesn't matter anyways. Even as someone who will defend the Big East, I would agree that I would take an undefeated USC and Texas over Louisville (or Pitt, would they have been in that position) to play in the BCS title game.
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Yes but Louisville is a Big East school. It will take a lot of convincing wins for the voters to deem them more deserving than what I will admit are the two most overrated teams this year (and I love USC!)