Four people own a bar, five counting Danny DeVito who joined a few episodes into the series (season two I think). Most people describe the show as Seinfeld-like, only way over the edge. It's one of the most politically-incorrect shows you'll ever see, including South Park. Think of a topic that most shows wouldn't make light of, and this one takes care of it. The character Charlie is one of the best TV characters in years.
http://youtube.com/watch?v=0SSHVucJ--A
http://youtube.com/watch?v=PD6J6kJ2lbU